Original article
Blood pressure and phosphate level in diabetic and non-diabetic kidney disease: Results of the cross-sectional “Low Clearance Consultation” study
Margarida Mendesa,, , Luis Resendeb, Alves Teixeirab, João Correiac, Gil Silvab
a SESARAM, Bom Jesus Health Centre, Madeira, Portugal
b SESARAM, Nephrology Department, Madeira, Portugal
c SESARAM, Internal Medicine Department, Madeira, Portugal
Received 15 February 2017, Accepted 23 February 2017
Abstract

Diabetic kidney disease features certain clinical and laboratorial characteristics that differ from chronic kidney disease of other etiologies. We performed a transversal study comparing some of these characteristics and assessed potential associations among blood pressure, plasma phosphate concentration and estimated glomerular filtration rate between patients with diabetic and non-diabetic chronic kidney disease.

We found a positive correlation between both systolic and diastolic blood pressure and the plasma phosphate concentration in the diabetic kidney disease group, but not in the non-diabetic group. Also, diastolic blood pressure was negatively correlated with the estimated glomerular filtration rate in the diabetic group, yet not in the non-diabetic group.

In conclusion, these data support the hypothesis of a close link between systolic and diastolic blood pressure and hyperphosphatemia, as well as between diastolic blood pressure and estimated glomerular filtration rate, in patients with diabetic kidney disease. Therapeutic approaches directed at these factors might prove to be important to delay the decline of renal function in the subgroup of patients with diabetic kidney disease.

Keywords
Diabetic kidney disease, Blood pressure, Phosphatemia

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